The No. 12 Ole Miss Rebels will try to bounce back from their first loss of the season when they go on the road to face the South Carolina Gamecocks. Ole Miss suffered a shocking loss to Kentucky at home last week, as the Wildcats pulled off a 20-17 win as a 17.5-point underdog. South Carolina had a bye week to prepare for this game following its 50-7 win over Akron two weeks ago. 

Kickoff is set for 3:30 p.m. ET on Saturday at Williams-Brice Stadium. Ole Miss is favored by 8.5 points in the latest South Carolina vs. Ole Miss odds, while the over/under is 53.5 points, per SportsLine consensus. Before entering any Ole Miss vs. South Carolina picks, you'll want to see the college football predictions from the model at SportsLine.

The model simulates every FBS college football game 10,000 times. Since its inception, it has generated a profit of well over $2,000 for $100 players on its top-rated college football picks against the spread. It also went a sizzling 6-0 on all top-rated college football picks in Week 5. Anyone who has followed it has seen STRONG returns.

The model has simulated South Carolina vs. Ole Miss 10,000 times and the results are in. We can tell you that the model is leaning Under, and it also says one side of the spread hits nearly 60% of the time!

So who wins South Carolina vs. Ole Miss, and which side of the spread hits nearly 60% of the time? Join SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its college football picks!